Treatment of Genital Warts
Over 30 papers have been published so far regarding the application of podophyllotoxin for the treatment of genital warts. Many reviews have appeared on this subject. Genital warts (Condyloma accuminata) are a kind of sexually transmitted disease (STD) caused by human papillomavirus (HPV). The application of highly purified podophyllotoxin cured almost all the warts completely in less than three treatments with tolerable side effects. Podophyllotoxin has thus proved to be an effective, comparatively safe drug for the treatment of genital warts. It is also very simple to apply and can be used for self-treatment. There are several reports regarding the formulation of podophyllotoxin as a cream versus solution. Podophyllotoxiri is also effective in the treatment of anogenital (AG) warts in children and molluscum contagiosum which is generally a self-limiting benign skin disease that effects mostly children and young adults.
The best mode of treating the none vascular wart is by excision. Whatever substitute is tried, the surgeon most commonly resorts to this at last. The ligature is quite as painful, or more so, and certainly much less efficient. Whether excision or the ligature be adopted, the surface that is exposed should be touched with caustic. With this precaution, the wart very often re-appears —without it, we may generally count on its doing so. When discharges co-exist with wart, proper means for arresting them should always be employed. Improvement of the secretions is desirable also–and for this, aperients, with the warm bath, and regulated diet are of service. When warts of the glans, or of the inner prepuce its angle, have occasioned phymosis, or those other can- sequences to which I have fully alluded, it becomes indispensable to divide the prepuce, or even to remove it. Indeed, if a patient with a prepuce naturally long, evinces a disposition to warts, which is not effectually prevented by cleanliness and the constant application of lint, I should strongly recommend the operation of division of the prepuce, or even that for the removal of some portion of it. I have performed both several times on this account, and the warts have subquentty ceased to appear. When adhesion’s have occurred between the inner prepuce and the warts, and ulcerated openings have formed in various parts of the prepuce, removal of a portion.
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